Clinical Trials

Do you have Parkinson’s disease and are currently able to walk without using any assistive device and are ages 50-74? If your answer to these questions is yes, you may qualify for our study. What will you do? You will wear activity monitors and a metabolic system; You will walk overground and on the treadmill. There is 1 lab visit that will last 2-3 hours. This study will advance the way we measure physical activity in people with Parkinson’s disease. Compensated with a $25 gift-card for participation. For more information, contact Jeffer on 205-975-9321 or via email enrl@uabmc.edu
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Healthy Adult Volunteers ages 18-89 needed for study Healthy individuals ages 18-89 are needed for a study exploring the reason why some individuals have an increased risk of forming calcium oxalate kidney stones. You don’t have to have kidney stones to participate. The study involves consuming prepared meals over 4 days and collecting urine and blood. Compensation up to $140. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.
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Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of Glucose on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians with no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians with no history of diabetes, heart problems or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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Do you have a family member diagnosed with RA or do you think you are at risk of developing RA? If so, you may be eligible to participate in a research study about the possible prevention of RA. Must be at least 18 years or older without a prior diagnosis of RA. For more information, please call 205-934-9843 or email lplove@uabmc.edu
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If you ages 18 and older AND have either heart failure (in the past 2 years) or a heart attack (in the past year) you may qualify for a research study. What happens in the study? • vaccination with either high dose (investigational for adults under the age of 65) OR standard dose flu shot, provided at no cost to you (once per year, up to 3 years); •monitoring any heart or lung related hospital visits; • telephone follow-up • optional blood draw. Patients who have already received their flu shot this year are not eligible to enroll. Participants will be compensated. For more information about how you can participate in INVESTED, please call the UAB Hypertension Program at 205-934-9281.
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April 10, 2017

Are you depressed?

Are you feeling sad, down, hopeless? Feeling guilty? Experiencing loss of interest in activities? Having difficulty concentrating? Sleeping too little or too much? 19-70 years old? In good physical health? If so, you may be eligible to participate in a research study. For more information, please call UAB Office of Psychiatric Research at 205-934-8336.
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This study will examine predictors of successful aging outcomes among adults and older adults with and without HIV. We are currently recruiting HIV-negative controls, thus to qualify, you must be HIV-negative, age 50 or older, be proficient in English, must not be mentally impaired or have significant neuromedical issues, and must consent to a blood draw. Eligible participants may be compensated up to $150 for a ~5-hour visit. For more information, please call 205-934-2862.
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Researchers in the School of Public Health are recruiting college students age 19 and older who smoke cigarettes (at least 5 cigarettes per day). Participants will take part in an educational counseling session. You do NOT have to want to quit smoking to participate. Participation involves coming to our center for one 30-minute orientation session, one 60-minute educational counseling session, and two 15-minute follow-up sessions. You will be asked to fill out some questionnaires, abstain from smoking overnight, and smoke a cigarette that we will provide you. You will be offered an 8-week supply of the nicotine patch that you may use if you wish. You will have the opportunity to be compensated a total of $75 cash for your participation. For more information, call our research staff at 205-975-7721.
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September 01, 2017

Paid men’s health study

Black men ages 16-35 needed for STI prevention study. We are looking for black or African American men to participate in a small confidential group discussion. The discussion is to understand the types of sexual health care services that are most desirable. To qualify, you must be male who has, at any time, had sex with another male. You will be compensated $50 for your participation. Please contact JP at (205) 975-1531 to see if you qualify.
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The UAB Neuroinflammation, Pain and Fatigue Lab is looking for individuals to take part in a research study. We will induce a temporary immune response and test how this affects fibromyalgia symptoms and markers of immune activity. You will be asked to come in for a screening session and, if eligible, two experimental sessions. You will be compensated up to $1025. Participants must have fibromyalgia, not be pregnant or currently planning to become pregnant, be without any significant medical conditions such as heart disease, and not currently using opioid medications. To find out more about this study, please call (205) 530-8006.
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Seeking healthy participants with no history or diagnosis of mental illness personally or in a first-degree relative — mom, dad, sibling. You must not require medication to treat an existing physical or mental illness/disorder. Individuals abusing alcohol or recreational drugs cannot participate as there will be intensive drug screening — both urine and blood. You must be ages 18-55 and weigh less than 190 lbs. Participants are needed to evaluate the effect of a drug called LY2150023 (Pomaglumetad or "POMA" for short) on a naturally occurring chemical called glutamate in the brain. We will also ask you to receive an intravenous infusion of a drug called ketamine. Study requirements: Screening (visit 1): determine your eligibility for the study, about 2 hours and includes drug testing, a complete medical and neurological check-up; Screening Ketamine MRI (visit 2): drug testing, MRI scan and ketamine infusion to determine study eligibility; Study Day 1 (visit 3): take study medicine in clinic, clinic evaluation, blood draw about 2 hours; Study Day 5 (visit 4): Clinical evaluation, blood draw and checkup about 2 hours; Study 10 (visit 5): Clinical evaluation, blood draw, drug testing, MRI scan and ketamine infusion about 5-6 hours. Three follow up phone calls. As a participant you will receive: $50 for visits 1, 3 and 4; $100 for visit 2; $300 for completion of visit 5 for a total of $600. For further information about the study and your eligibility, please contact Kristen at 996-9813.
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Our study is currently recruiting single primary caregivers of a 3-8 year old child to fill out 2 questionnaires about health and weight. Eligible participants will be compensated $10 for their time. Call 205-975-7721 for more information or to see if you are eligible to participate.
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Healthy African American or Caucasian men and women ages 18-40 needed to participate in a research study about the effects of glucose on a protein in your blood — this protein is related to heart disease. Must have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please email Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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Do you have a child age 15-18? Is your child in good health without diabetes, thyroid dysfunction, autoimmune diseases, mental illness, or taking medications affecting weight? If so, your child may be eligible to participate in a research study on early life stress, obesity, and depression. For more information, please call the UAB Office of Psychiatric Research at (205) 975-4207 or (205) 934-8336. Compensation provided up to $140.
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Do you have a child age 12-18 with depression? Is your child experiencing any of the following symptoms: sadness or hopelessness, persistent irritability or anger, feelings of guilt, changes in appetite or weight, loss of interest in activities, difficulty concentrating, too little or too much sleep, thoughts of death or suicide, reckless behavior or increased boredom. If so, your child may be eligible to participate in a research study on early life stress, obesity, and depression. For more information, please call the UAB Office of Psychiatric Research at (205) 975-4207
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June 06, 2017

Got gout?

If you have been diagnosed with gout, you may qualify to participate in one of our Gout research studies. Treatment and compensation for your time is provided per study visit. Please call Stephanie at 205-934-1444 or sbiggers@uabmc.edu.
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If you are age 18 or older and healthy (not suffering from any serious clinical condition) you may be eligible to participate in a study to determine bioenergetic health. Participants will answer a short questionnaire and have blood collected (20ml ie. 2-3 tubes). Compensation ($25) after blood draw will be provided per study visit. For more information, please email mitolab@uabmc.edu.
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Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians and have no history of diabetes, heart problems, or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of glucose on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians and have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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The UAB Division of Rheumatology and Immunology is conducting a study to research the effects of Rheumatoid Arthritis on muscle strength and insulin. To qualify, you must be between the ages of 35 and 65, not be diagnosed with diabetes or any other illness that may impair evaluation of study outcomes, and do not engage in a strength training program or vigorous exercise. All participants will be required to come to UAB for testing on 3 or more occasions and qualified RA participants will receive a 15-week regimen of the study drug. There is no charge for participation and all participants will receive compensation. For more information, and to see if you might be eligible to join, call (205) 934-4021.
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UAB is currently offering a no-cost research treatment program for those who want to stop using cocaine. This study combines medication and counseling treatment. If you use cocaine and would like to stop, please call UAB at (205) 975-7721.
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African American, healthy adults, age 85 and older needed for a study about healthy aging We are looking for those interested in participating in a UAB study about healthy aging. You may be eligible if you have no major physical disabilities and are independent in basic life activities. Participants will be compensated for visits. Call 205-975-7017 for more information and to see if you qualify.
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Are you a breast cancer survivor having difficulty walking? Do you have any lower-body pain that is restricting your mobility? If so, you may be interested in taking part in an exercise training intervention. UAB researchers are looking for overweight women  - age 18-70 with a body mass index between 30-45 kg/m2 - with a history of breast cancer to participate in a novel exercise training study. Volunteers will be asked to attend two assessment sessions: an initial assessment and after 8 weeks of exercise to collect information about your health status. Further eligibility screening will be conducted by telephone. Volunteers must reside in or near Jefferson County. The study will evaluate a novel exercise training strategy designed to mimic exercise at higher altitude to support improved health and mobility among breast cancer survivors. Contact Dr. Stephen J. Carter, 205-975-0269 or carters@uab.edu; or the UAB Exercise and Cancer Research Team, 205.934.5466 or moveforward@uab.edu; to learn more.
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We are looking for healthy older adults who are interested in participating in a study about healthy aging. You may be eligible if you have no major physical disabilities, are independent in basic life activities, and are 85 years or older. Participants will be compensated. Call 205-975-7017 for more information and to see if you qualify.
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The UAB Neuroinflammation, Pain and Fatigue Lab is looking for individuals to take a low dose of naltrexone or a placebo for 6 months. Every participant will receive the drug at some point during the study. You will be asked to come in for a screening session; to complete a daily symptom questionnaire and to provide blood samples during the 6-month period. If eligible, you will be compensated up to $425. Participants must: Have moderate to severe chronic fatigue (for at least 12 months); Not be pregnant or currently planning to become pregnant; Be without any significant medical conditions such as heart disease; and Not currently using opioid medications. For more about this study, call (205) 530-8006.
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Overweight/obese adolescents ages 15-17 with an iPhone or Android cell phone who sleep less than an average of 8 hours per night and their parent wanted for a study of the effects of sleep on adolescents’ overall health. Requires 8 visits to UAB laboratory and 3 blood draws over a 4 month period. Participants and their parent are eligible to receive a total payment of $400 ($320 for participants and $80 for their parent). For more information call 205-975-4205 or email elliottl@uab.edu.
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Are you ages 18-75? Are you currently taking medication specifically for Pulmonary Arterial Hypertension, also known as Pulmonary Hypertension? You may qualify for participation in the ongoing LIBERTY research study. If you would like more information, please contact the UAB Cardiovascular Clinical Trial Unit, 205-975-9964.

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We are currently seeking individuals diagnosed with spinal cord injury (SCI) for a research study evaluating diet. The purpose of this study is to determine if a low carb or low fat diet is better for helping adults with SCI: 1) stick to their diet, 2) improve their body composition, and 3) lower their cardiometabolic risk factors (such as diabetes, heart disease, or stroke). This study is for adults with SCI ages 21-60. Participation is free, and compensation is provided. For more information, please call Ashley Sineath at 205-403-5510 or email at asineath@uab.edu
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You could be a candidate for a research study evaluating a new procedure for treating high blood pressure. Are you age 18-75? Are you willing to stop or change your current blood pressure medicine for a short time if supervised by a doctor? If yes and you want more information regarding the RADIANCE-HTN STUDY, please contact the UAB Hypertension Clinic at bloodpressure@uab.edu. Participants will be reimbursed for travel and study visits expenses.
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ASPIRE is a National Institutes of Health (NIH) study that compares three surgical procedures that are currently used to repair vaginal prolapse.  Women who have had a hysterectomy, feel or see a vaginal bulge and desire further evaluation may be eligible. For more information, call 934-5498. Compensation is provided.
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We are currently seeking cardiac surgical patients to participate in the LEVO-CTS research study. The purpose of the study is to evaluate an investigational drug with the potential to improve outcomes in patients undergoing coronary artery bypass and/or heart valve surgery. Minimum eligibility requirements: Must be 18 years or older, your physician has diagnosed you with coronary vessel disease requiring bypass surgery and/or the need for heart valve surgery. Talk to your cardiologist or your heart surgeon for additional information. Questions can also be answered by Alicia Kindred or D'Netria Jackson at 205-934-4711 or 205-975-2088.
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This study will examine the effectiveness of a group exercise class on the health and function adults age 18-65 with a history of stroke. You will be randomly assigned to one of two groups; Movement2Music or a waitlist group who will complete a home-based exercise intervention. Email caseyh@lakeshore.org or call 205-313-7455 for more information. Participation is free, and compensation is provided.

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Overweight/obese adolescents ages 15-17 with an iPhone or Android phone who sleep less than an average of 8 hours per night and their parent wanted for a study of the effects of sleep on adolescents’ overall health. Requires 8 visits to UAB laboratory and 3 blood draws over a 4 month period. Participants and their parent are eligible to receive a total payment of $400 ($320 for participants and $80 for their parent). For more information call 205-934-2241 or email elliottl@uab.edu.

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In our study of patients with resistant hypertension, we have shown that vascular function improves with the use of spironolactone, a mineralocorticoid receptor antagonist. Spironolactone has also been shown to reduce urinary protein loss in patients with chronic kidney disease. We are looking for men and women, ages 19-65, with Stage III CKD, non-diabetic or who have controlled diabetes, and who are not currently taking spironolactone or amiloride. The study lasts 16 weeks, with six visits, and compensation and parking will be provided for all six visits. If interested, please contact Cassidy Clevenger at (205) 934-6745.
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Are you concerned about your bone and joint health? Men and women age 45-69 are needed for a Bone and Joint Health Study, a study about how physical activities and other factors affect the health of your bones and joints.  Compensation is provided.  Call 205-975-7223, Option 2 for more information!
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Women age 18 and older needed for study of new treatment for vaginal yeast infection. Must have untreated yeast infection at time of enrollment. Study participation lasts for one month. Free medication and exams.  Reimbursement available for enrollment and follow-up visits, up to $200. For more information call Joy or Sanquetta at 205-996-2780.
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Local physicians are part of a larger clinical trial utilizing an investigational medical device for people with post-amputation pain. If you are experiencing moderate to severe post-amputation pain not controlled by medication, we invite you to learn more. Qualifications for the study include: one amputated lower limb; frequent and recurring amputation pain; willingness to undergo implant surgery; and age 21 or older. For participation information, please email aliciakindred@uabmc.edu, jpough@uabmc.edu or call 934-4711 or 975-2847 to speak with Alicia Kindred (Study Coordinator) or Joseph Pough (Research Assistant).
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You may qualify for a research study in the UAB Department of Psychiatry and Behavioral Neurobiology if you have never been diagnosed with a mental illness. Call 975-4207 for more information. Compensation provided.
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You may qualify for a research study in the UAB Department of Psychiatry and Behavioral Neurobiology. Call 975-4207 for more information. Compensation provided.
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The UAB Office of Psychiatric Research is conducting a study examining the relationship between early life stress, depression, and glucose metabolism. In order to qualify, you must have no history of anxiety, psychosis, mania, substance dependence within a year. You must also have no history of endocrine, cardiovascular, or inflammatory diseases. To see if you may qualify, please call (205) 975-4207.
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Are you in good physical health with no history of psychiatric disorders? You may be eligible for a research study examining the relationship between early life stress, depression, and glucose metabolism. Compensation provided. For more information, please contact the UAB Office of Psychiatric Research at (205) 975-4207
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Healthy non-smokers 65 and older needed for pneumonia study. Compensation available. Call the Lung Health Center. 934-5555
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Have you had recurrent BV (bacterial vaginal infections) 2 or more times in the past 12 months?  We are conducting a sexual partner study for treatment of the female and male sexual partners as a way to prevent BV. Medication at no cost to you. Couples can receive up to $300. Joy, 205-996-2780
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Are you in good physical health? Never been diagnosed with a psychiatric condition? Compensation provided. For more information, call UAB Office of Psychiatric Research at 975-8542.
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We are inviting you to participate in the D.I.A.L. physical activity program for 12 weeks at no cost to you. What is it? Receive 12-weeks of physical activity information over the phone. Who can join? Any healthy adult age 21 or older and you do not have to currently be physically active to participate. Why be involved? Contribute to cancer prevention research and receive compensation for your involvement. Call 205-934-0504 to see if you qualify for the program.
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You  may qualify to participate in a national 8-week research study to evaluate the safety and efficacy of an investigational medication to treat patients with resistant hypertension. Are you 40-85 years old? Do you have high blood pressure? Eligible study participants will receive study medications, blood pressure checks, study related physical exams, laboratory tests, ABPM and ECG at no cost. Participants will be compensated. For more information, please call the UAB Hypertension Program at (205) 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.
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A 24-month research study is being conducted by the UAB School of Dentistry to determine the effectiveness of a commercially available tooth colored dental filling materials bonded on the sides of teeth with three adhesives. Enrollment in the study requires that the subject be available for the 24-month study period. Screening appointments now are available and subjects needing fillings on the sides of their teeth are likely candidates. The fillings are free and a monetary incentive is paid at each recall visit. To determine if you are eligible for this study, call LaTara 996-5747.
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You may qualify to participate in an international research study to evaluate the safety and tolerability of an investigational drug for patients with type 2 diabetes and kidney disease. Are you at least 18 years old? Do you have type 2 diabetes mellitus and a clinical diagnosis of kidney disease? Eligible study participants will receive study medications, blood pressure checks, physical exams, laboratory tests and ECG at no cost. Participants will  be reimbursed for time and travel. For more information, call the UAB Hypertension Program at 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.
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