Two physician-scientist trainees in the Department of Pathology participated in the UAB Global Health Symposium on October 29 and 30. Chiamaka Umah, M.D., PGY3, and Falone Amoa, M.D., M.S., a PGY5 and Ph.D. candidate in the laboratory of Upender Manne, Ph.D., M.S., participated in a range of engaging sessions to gain insights into innovative applications of artificial intelligence across diagnostics, health systems, disease surveillance, and more.

Chronic granulomatous fungal sinusitis is a rare, debilitating infection characterized by an enlarged mass in the nasal cavity or sinuses, facial pain and swelling, eye bulging, vision problems, headache and nasal congestion. While most cases are found in subtropical regions of Sudan, India, Pakistan and Saudi Arabia caused by Aspergillus flavus, a pathogenic fungus, cases have recently been identified in the Southeastern United States caused by Curvularia, an emerging pathogen.

Sometimes it’s difficult to make time for hobbies outside of work. Doing so, however, can reduce stress and improve mental and physical health. The Department of Pathology’s Committee for Access and Engagement is on a mission to provide a welcoming environment that fosters the professional and personal development of faculty, staff and trainees. This month, several members from the committee shared some of their favorite hobbies, and why they find them meaningful.

UAB Medicine’s Leadership Development Office (LDO) celebrated seven distinguished faculty members from the seventh cohort of the Sharing Authentically to Inspire and Lead (SAIL) program at a graduation ceremony on Tuesday, Oct. 21. The program, facilitated by Celeste Morgan, Ph.D., CDMS, senior leadership development specialist, is designed to help early-career faculty strengthen their leadership skills, refine their academic identities, and chart clear, sustainable paths toward long-term success.

The Department of Pathology is thrilled to announce the winners of its inaugural 2025 Chair’s Excellence Awards. These awards celebrate faculty members in the Department of Pathology who exude clinical, research and educational excellence. This year’s winners are Hua Guo, M.D., M.S., Chair’s Award for Clinical Excellence, Ming He, M.D., Ph.D., Chair’s Award for Research Excellence, and Valeria Dal Zotto, M.D., Chair’s Award for Educational Excellence. Winners are chosen by Cristina Magi-Galluzzi, M.D., Ph.D., Robert and Ruth Anderson Endowed Chair.

A recent study published in Redox Biology by researchers from the UAB Department of Pathology revealed that too much of a good thing, specifically excessive antioxidants, can lead to heart damage. Traditionally, antioxidants and reducing agents have been found to protect cells. The new study “Reductive stress induces unresolved ER stress and proteotoxic cardiomyopathy” authored by Sini Sunny, Ph.D., postdoctoral fellow, and Rajasekaran Namakkal-Soorappan, Ph.D., an associate professor in the Division of Molecular and Cellular Pathology, challenges this notion with their findings.

Joanne Murphy-Ullrich, Ph.D., Professor Emerita, Division of Molecular and Cellular Pathology, recently received a patent coin to honor her hard work and dedication as a UAB inventor. The patent coin recognition program is led by the UAB Harbert Institute for Innovation and Entrepreneurship. Beginning this past spring, UAB researchers who are named on a full patent will receive a ceremonial coin stamped with their name and patent number.

Several members from the UAB Department of Pathology ran on October 11 in Equal Access Birmingham's (EAB) 10th Annual Heart + Sole 5K Run, promoting health and wellness in the Birmingham community. All proceeds from the fundraiser support EAB operations and the EAB Clinic to provide medications and medical services for patients. This year was the run's first time returning in person since before the pandemic. 

The 2025 Tri-State Pathology Conference took place October 4-5 at the New Orleans Marriot in Louisiana, hosted by the Louisiana Pathology Society, in conjunction with the Mississippi Association of Pathologists and the Alabama Association of Pathologists. 

The UAB HSF Robert B. Adams Cytology Laboratory opened recently in Montgomery, Alabama, as part of the Department of Pathology’s Community Practice Pathology Program (CPPP). This laboratory space was donated by the Adams family and renovated by the Department of Pathology. Its opening has been seven years in the making.

The UAB Medical Scientist Training Program (MSTP) hosted the Southeastern Medical Scientist Symposium (SEMSS) on September 27-28 at the UAB Marnix E. Heersink Institute for Biomedical Innovation. SEMSS is a student-run conference designed to bring together both current and aspiring physician-scientists from around the southeastern United States and beyond to share research and build community.

Girish Melkani, Ph.D., professor in the Department of Pathology, has been named the latest recipient of the school’s Featured Discovery award. This recognition celebrates notable research contributions made by faculty and highlights the impact of their scientific advancements.

About half of Americans between 45 and 84 have atherosclerosis without knowing it. Diseases linked to atherosclerosis are the leading cause of death in the United States. The condition develops when fats, cholesterol and other substances form plaque in the arteries. As plaque builds, arteries narrow and block blood flow, or can burst, which may lead to blood clotting. The initiation and progression of atherosclerosis are largely driven by genetic and environmental risk factors, but in between, how epigenetic regulation contributes to this pathogenesis remains largely unknown.

The UAB Department of Pathology recently funded travel awards to two trainees, Sajal Kumar Halder and Dr. Kenneth Long, who will present their research at national meetings this year.

Michel Kmeid, M.D., an assistant professor in the Division of Anatomic Pathology, will serve as medical director of the gross room and frozen section lab, effective October 1.

The UAB Department of Pathology celebrated the 30th year of its Paulette Shirey Pritchett Endowed Lecture in Pathology on September 25 with an outstanding lecture by Mark T. Gladwin, M.D., Dean, University of Maryland School of Medicine, Vice President for Medical Affairs, University of Maryland, and the John Z. Akiko K. Bowers Distinguished Professor and Dean. Gladwin delivered the talk, titled, “Translating Redox Biology to Medicine: Lessons Learned, Taking Risks, and Going NO Where.”

Granzyme K (GzmK), a family of granzymes implicated in age-associated inflammatory disease, plays a key role in driving chronic inflammation by causing cell death. Despite its significant impact on diseases like asthma, psoriasis and atherosclerosis, current therapies lack focus on GzmK.

Several Research and Clinical Experience in Pathology (RaCE4Path) students presented posters at the 2025 UAB Heersink School of Medicine Dale J Benos Medical Student Research Day on September 15 and the UAB Undergraduate Research Expo on July 24.

In 2016, the rare disease Zhu-Tokita-Takenouchi-Kim, or ZTTK Syndrome, was discovered by Erin Eun Young Ahn, Ph.D., a professor in the UAB Department of Pathology’s Division of Molecular and Cellular Pathology, alongside her research team. ZTTK is primarily identified in children and is characterized by intellectual disability, delayed musculoskeletal development and multi-organ anomalies, and is caused by loss of function in the SON gene. This gene creates a DNA and RNA binding protein, SON, that is required for the body to grow and develop naturally.

The UAB Department of Pathology boasts a long legacy of fostering physician-scientists who are skilled both in clinical practice and research. These practitioners bridge the crucial gap between the lab and patient care, using clinical experience to drive research leading to new treatments and therapies. Their efforts target individualized medicine, propel public health breakthroughs and ensure that scientific discoveries are translated directly to the bedside.